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Anti-aging and related articles
 

Clinical references

On this page you will find links below to pages dealing with specific areas on which the formulators worked when putting together our effective anti-wrinkle and anti-aging Créme de Vie product.

anti-wrinkle anti-aging

Below that, you will find the clinical references which are referred to in our on-line documentation.

anti-wrinkle and anti-aging

Clinical references

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  3. Benedetto, A.V. The cosmetic use of Botulinum neurotoxin type A. Int. J. Derm. 38, 641-655 (1999)

  4. Becker-Wegerich, P.M., Rauch, L. and Ruzicka, T. Botulinum toxin a successful decollete rejuvenation. Dermatol. Surg. 28, 168-171 (2002).

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  6. Johnson, E.A. Clostridial toxins as therapeutic agents: Benefits of nature's most toxic proteins. Annu. Rev. Microbiol. 53, 551-575 (1999).

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  8. Gutierrez, L.M., Canaves, J., Ferrer-Montiel, A., Reig, J.A., Montal, M. and Viniegra, S. A peptide that mimics the carboxy-terminal domain of SNAP-25 blocks Ca 2'-dependent exocytosis in chrornaffin cells. FEBS Lett. 372, 39-43 (1995).

  9. Gutierrez, L.M., Viniegra, S., Rueda, J., Ferrer-Montiel, A.V., Canaves, J.M. and Montal, M. A peptide that mimics the C-terminal sequence of SNAP-25 inhibits secretory vesicle docking in chrornaffin cells. J. Biol. Chem. 272, 2634-2639 (1997).

  10. Ferrer-Montiel, A.V, Gutierrez, L.M., Apland, J.P., Canaves, J.M., Gil, A., Viniegra, S., Biser, J.A., Adler, M. And Montal, M. The 26-mer peptide released from SNAP25 by botulinum neurotoxin E inhibits vesicle docking. FEBS Lett. 435, 84-88 (1998).

  11. Blanes-Mira, C., lb6hez, C., Fernandez-Ballester, G., Planells-Cases, R., P6rezPay6, E., Ferrer-Montiel, A. (2001). Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue. Biochemistry 40, 2234-2242 (2001).

  12. Ferrer-Montiel, AN., Canaves, J.M., DasGupta, BR, Wilson, M.C. and Montal, M. Tyrosine phosphorylation modulates the activity of clostridial neurotoxins. J. Biol. Chem. 271, 31, 18322-18325 (1996).

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  18. Nexbase 2006 FG: Preliminary toxicity study by dietary administration to F-344 rats for four weeks, T.J.Lawler, Pharmaco: LSR, UK, 22.12.1993. 

  19. Nexbase 2006 FG: Toxicity study by dietary administration to F-344 rats for 13 weeks followed by a 4 week reversibility period, S.Cooper, Pharmaco:LSR, UK, November 1994.

  20. Huidtesten met Neste Nexbase 2004FG, Nexbase 2006FG en Nexbase 2008FG. Prof. A.Goossens, Contactallergie-Dermatologie, U.Z Sint Rafaël, Leuven, Belgium, May 1999. 

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  22. 3 H- NEXBASE™ 2006FG, In Vitro dermal penetration study in human skin. Huntingdon Life Sciences Ltd, UK, February 1999.

  23. 3 H- NEXBASE™ 2006FG, Percutaneous absorption study in the rat. Huntingdon Life Sciences Ltd, UK, May 1999.

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